Grading melanocytic dysplasia in paraffin wax embedded tissue by the nucleic acid index
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چکیده
منابع مشابه
Grading melanocytic dysplasia in paraffin wax embedded tissue by the nucleic acid index.
BACKGROUND Although nucleic acid derangements are the hallmark of melanocytic dysplasia, the gold standard for its diagnosis remains the microscopic evaluation of haematoxylin and eosin stained slides. However, light microscopy is subjective and crucial genomic changes do not always show as changes in histology. AIMS To introduce the nucleic acid index (NAI) as a means of analysing nucleic ac...
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The use of gas chromatography and mass spectrometry with selected ion monitoring detected tuberculostearic acid (TBSA) in 10 of 12 formalin fixed, paraffin wax embedded nasopharyngeal and head and neck biopsy specimens from patients with confirmed tuberculosis and carcinoma, and in one of 50 control specimens (giving a sensitivity of 83% and a specificity of 98%). The two false negative cases h...
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A method for identifying Helicobacter pylori using a non-isotopic in situ hybridisation technique is described. A probe generated by polymerase chain reaction (PCR) with primers directed against parts of the Helicobacter pylori 16SrRNA sequence was used. Paraffin wax embedded gastric biopsy specimens from patients with and without gastritis were hybridised with the probe, and the method was sho...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2005
ISSN: 0021-9746
DOI: 10.1136/jcp.2005.026559